What is Chronic Kidney Disease ?
Your kidneys, each just the size of a computer mouse, filter all the blood in your body every 30 minutes. They work hard to remove wastes, toxins, and excess fluid.(1) Your kidneys also remove acid that is produced by the cells of your body and maintain a healthy balance of water, salts, and minerals—such as sodium, calcium, phosphorus, and potassium—in your blood. Without this balance, nerves, muscles, and other tissues in your body may not work normally. Your kidneys also make hormones that help control your blood pressure and make red blood cells.(2) Diabetes and high blood pressure are the most common causes of chronic kidney disease (CKD). (5) Approximately 1 in 3 adults with diabetes, and 1 in 5 adults with high blood pressure, may have chronic kidney disease. (4)
With chronic kidney disease (CKD), kidneys become damaged and over time may not clean the blood as well as healthy kidneys. If kidneys don’t work well, toxic waste and extra fluid accumulate in the body and may lead to high blood pressure, heart disease, stroke, and early death.(3) Chronic kidney disease (CKD) causes loss of kidney function over time and may lead to kidney failure or end-stage kidney disease (ESKD).(4)
According to the Centers for Disease Control (CDC):
• More than 1 in 7 US adults—about 35.5 million people, or 14%—are estimated to have CKD.
• As many as 9 in 10 adults with CKD do not know they have it.
• Kidney diseases are a leading cause of death in the United States.
• About 360 people begin treatment for kidney failure (dialysis or kidney transplant) every day.
Kidney disease is often “progressive”, which means it gets worse over time. The damage to your kidneys causes scars and is permanent.(7) Kidney failure means that your kidneys have lost most of their ability to function—less than 15 percent of normal kidney function. If you have kidney failure, you will need treatment to maintain your health.(8)
CKD Symptoms
Signs and symptoms of chronic kidney disease develop over time if kidney damage progresses slowly. Loss of kidney function can cause a buildup of fluid or body waste or electrolyte problems. Depending on how severe it is, loss of kidney function can cause:
- Nausea
- Vomiting
- Loss of Appetite
- Fatigue and Weakness
- Sleeping problems
- Urinating more or less
- Decreased mental sharpness
- Muscle cramps
- Swelling of feet and ankles
- Dry, itchy skin
- High blood pressure
- Shortness of Breath
- Etc…
Stem Cells For Chronic Kidney Disease
There are different approaches to stem cell therapy for CKD. One approach involves using adult stem cells (MSCs), which have the ability to differentiate into various sources, such as bone marrow, adipose tissue, or umbilical cord blood. These cells can be injected into patient’s bloodstream or directly into the kidney, where they may promote tissue repair, reduce inflammation, and stimulate the growth of new blood vessels.

Stem cell therapy for kidney disease involves the use of stem cells to repair or regenerate damaged kidney tissues. The goal is to improve kidney function and reduce symptoms associated with kidney disease
Stem cells can differentiate into different cell types including kidney cells. They can migrate to the damaged areas of the kidney to help regrow healthy cells. They have the ability to travel to the site of injury. Our studies show reduced inflammation, and the process of regeneration of healthy and more potent cells in many cases
Stem cell therapy has shown promise in the treatment of various kidney diseases, including chronic kidney disease, acute kidney injury, polycystic kidney disease among others.
Stem cells can be administered through various methods, such as intravenous injection, direct injection into the kidney or through targeted delivery using catheters
The potential benefits of stem cell therapy for kidney disease include, improved kidney function, reduced symptoms, decreased inflammation, slowed disease progression, and enhanced quality of life. However, effectiveness can vary depending on the individual and the specific kidney disease
Disease and Conditions that cause chronic kidney disease:
- Type 1 or type 2 diabetes
- High-blood pressure
- Recurrent kidney condition
- Etc..
Risks Factors
- Diabetes
- High-blood pressure
- Heart (cardiovascular) disease
- Smoking
- Obesity
- Family history of kidney disease
- Abnormal kidney structure